Neurofilament (NEFM) Mouse Monoclonal Antibody [Clone ID: LBI1A4]
Product Specifications
Background
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
Synonyms
NEF3; NF-M; NFM
Gene Name
Neurofilament medium chain
Gene ID
4741
UniProt
P07197
Conjugation
Unconjugated
Related Pathways
Amyotrophic lateral sclerosis (ALS)
Field of Research
Amyotrophic lateral sclerosis (ALS)
Concentration
1 mg/ml
Dilution
WB 1:1000 -1:4000, IF 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
NEFM
Overview
NEFM mouse monoclonal antibody, clone LBI1A4
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4741
Uniprot URL
https://www.uniprot.org/uniprot/P07197
Curated Selection
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