MMP13 Mouse Monoclonal Antibody [Clone ID: LBI3F5]
Product Specifications
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
Synonyms
CLG3; MANDP1; MDST; MMP-13
Gene Name
Matrix metallopeptidase 13
Gene ID
4322
UniProt
P45452
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:4000, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Protease
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
MMP13
Overview
MMP13 mouse monoclonal antibody, clone LBI3F5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4322
Uniprot URL
https://www.uniprot.org/uniprot/P45452
Curated Selection
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