CD163 Mouse Monoclonal Antibody [Clone ID: LBI3B4]
Product Specifications
Background
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Synonyms
M130; MM130; SCARI1
Gene Name
CD163 molecule
Gene ID
9332
UniProt
Q86VB7
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:200~4000, IHC 1:150, IF 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Secreted Protein, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CD163
Overview
CD163 mouse monoclonal antibody, clone LBI3B4
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=9332
Uniprot URL
https://www.uniprot.org/uniprot/Q86VB7
Curated Selection
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