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Cytochrome C Oxidase subunit VIc (COX6C) Mouse Monoclonal Antibody [Clone ID: LBI4B11]

Product Specifications

Background

Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. [provided by RefSeq, Jul

Synonyms

Cytochrome c oxidase subunit VIc; cytochrome c oxidase subunit VIc preprotein

Gene Name

Cytochrome c oxidase subunit 6C

Gene ID

1345

UniProt

P09669

Conjugation

Unconjugated

Related Pathways

Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

Field of Research

Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

Concentration

1 mg/ml

Dilution

WB 1:4000, IHC 1:150, IF 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

COX6C

Overview

COX6C mouse monoclonal antibody, clone LBI4B11

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=1345

Uniprot URL

https://www.uniprot.org/uniprot/P09669

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