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Granzyme B (GZMB) Mouse Monoclonal Antibody [Clone ID: LBI4E4]

Product Specifications

Background

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008]

Overview

GZMB (Granzyme B) mouse monoclonal antibody, clone LBI4E4

Synonyms

C11; CCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA1; CTSGL1; HLP; SECT

Gene Name

Granzyme B

Gene ID

3002

UniProt

P10144

Conjugation

Unconjugated

Related Pathways

Allograft rejection, Autoimmune thyroid disease, Graft-versus-host disease, Natural killer cell mediated cytotoxicity, Type I diabetes mellitus

Field of Research

Allograft rejection, Autoimmune thyroid disease, Graft-versus-host disease, Natural killer cell mediated cytotoxicity, Type I diabetes mellitus

Concentration

1 mg/ml

Dilution

WB 1:2000, IHC 1:150, IF 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Protease

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

GZMB

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=3002

Uniprot URL

https://www.uniprot.org/uniprot/P10144

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