CA12 Mouse Monoclonal Antibody [Clone ID: LBI1A6]

Product Specifications

Background

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Overview

CA12 mouse monoclonal antibody, clone LBI1A6

Synonyms

CAXII; HsT18816

Gene Name

Carbonic anhydrase 12

Gene ID

771

UniProt

O43570

Conjugation

Unconjugated

Related Pathways

Nitrogen metabolism

Field of Research

Nitrogen metabolism

Concentration

1 mg/ml

Dilution

WB 1:500, IHC 1:150

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.