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CD1C Mouse Monoclonal Antibody [Clone ID: LBI2F1]

Product Specifications

Background

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul

Synonyms

BDCA1; CD1; CD1A; R7

Gene Name

CD1c molecule

Gene ID

911

UniProt

P29017

Conjugation

Unconjugated

Related Pathways

Hematopoietic cell lineage

Field of Research

Hematopoietic cell lineage

Concentration

1 mg/ml

Dilution

WB 1:200 - 1:2000, IF 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

CD1C

Overview

CD1C mouse monoclonal antibody, clone LBI2F1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=911

Uniprot URL

https://www.uniprot.org/uniprot/P29017

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