CD1C Mouse Monoclonal Antibody [Clone ID: LBI2F1]
Product Specifications
Background
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul
Synonyms
BDCA1; CD1; CD1A; R7
Gene Name
CD1c molecule
Gene ID
911
UniProt
P29017
Conjugation
Unconjugated
Related Pathways
Hematopoietic cell lineage
Field of Research
Hematopoietic cell lineage
Concentration
1 mg/ml
Dilution
WB 1:200 - 1:2000, IF 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CD1C
Overview
CD1C mouse monoclonal antibody, clone LBI2F1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=911
Uniprot URL
https://www.uniprot.org/uniprot/P29017
Curated Selection
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