OTUB1 Mouse Monoclonal Antibody [Clone ID: LBI2H1]

Product Specifications

Background

The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Overview

OTUB1 mouse monoclonal antibody, clone LBI2H1

Synonyms

HSPC263; OTB1; OTU1

Gene Name

OTU deubiquitinase, ubiquitin aldehyde binding 1

Gene ID

55611

UniProt

Q96FW1

Conjugation

Unconjugated

Concentration

1 mg/ml

Dilution

WB 1:2000, IHC 1:150, IF 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Protease

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.