Cbl c (CBLC) Mouse Monoclonal Antibody [Clone ID: LBI4E3]
Product Specifications
Background
This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
Synonyms
CBL-3; CBL-SL; RNF57
Gene Name
Cbl proto-oncogene C
Gene ID
23624
UniProt
Q9ULV8
Conjugation
Unconjugated
Related Pathways
Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Ubiquitin mediated proteolysis
Field of Research
Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Ubiquitin mediated proteolysis
Concentration
1 mg/ml
Dilution
WB 1:500, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CBLC
Overview
CBLC mouse monoclonal antibody, clone LBI4E3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=23624
Uniprot URL
https://www.uniprot.org/uniprot/Q9ULV8
Curated Selection
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