ERp57 (PDIA3) Mouse Monoclonal Antibody [Clone ID: LBI4D7]
Product Specifications
Background
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. [provided by RefSeq, Jul 2008]
Overview
PDIA3 (ERp57) mouse monoclonal antibody, clone LBI4D7
Synonyms
ER60; ERp57; ERp60; ERp61; GRP57; GRP58; HEL-S-93n; HEL-S-269; HsT17083; P58; PI-PLC
Gene Name
Protein disulfide isomerase family A member 3
Gene ID
2923
UniProt
P30101
Conjugation
Unconjugated
Related Pathways
Antigen processing and presentation
Field of Research
Antigen processing and presentation
Concentration
1 mg/ml
Dilution
WB 1:1000, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PDIA3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2923
Uniprot URL
https://www.uniprot.org/uniprot/P30101
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