ATIC Mouse Monoclonal Antibody [Clone ID: LBI4A10]

Product Specifications

Background

This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq]

Overview

ATIC mouse monoclonal antibody, clone LBI4A10

Synonyms

AICAR; AICARFT; HEL-S-70p; IMPCHASE; PURH

Gene Name

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

Gene ID

471

UniProt

P31939

Conjugation

Unconjugated

Related Pathways

Metabolic pathways, One carbon pool by folate, Purine metabolism

Field of Research

Metabolic pathways, One carbon pool by folate, Purine metabolism

Concentration

3.51 mg/ml

Dilution

WB 1:500~1000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Stem cell - Pluripotency

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.