ATIC Mouse Monoclonal Antibody [Clone ID: LBI2C10]
Product Specifications
Background
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq]
Overview
ATIC mouse monoclonal antibody, clone LBI2C10
Synonyms
AICAR; AICARFT; HEL-S-70p; IMPCHASE; PURH
Gene Name
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Gene ID
471
UniProt
P31939
Conjugation
Unconjugated
Related Pathways
Metabolic pathways, One carbon pool by folate, Purine metabolism
Field of Research
Metabolic pathways, One carbon pool by folate, Purine metabolism
Concentration
1.09 mg/ml
Dilution
WB 1:500~2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Stem cell - Pluripotency
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
ATIC
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=471
Uniprot URL
https://www.uniprot.org/uniprot/P31939
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