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Calpastatin (CAST) Mouse Monoclonal Antibody [Clone ID: LBI1E7]

Product Specifications

Background

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Synonyms

BS-17; PLACK

Gene Name

Calpastatin

Gene ID

831

UniProt

P20810

Conjugation

Unconjugated

Concentration

0.62 mg/ml

Dilution

WB 1:2000, IHC 1:150, FLOW 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

CAST

Overview

CAST (Calpastatin) mouse monoclonal antibody, clone LBI1E7

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=831

Uniprot URL

https://www.uniprot.org/uniprot/P20810

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