FMRP (FMR1) Mouse Monoclonal Antibody [Clone ID: LBI2C3]

Product Specifications

Background

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1) . Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]

Overview

FMR1 (FMRP) mouse monoclonal antibody, clone LBI2C3

Synonyms

FMRP; FRAXA; POF; POF1; POFX

Gene Name

FMRP translational regulator 1

Gene ID

2332

UniProt

Q06787

Conjugation

Unconjugated

Concentration

0.96 mg/ml

Dilution

WB 1:200~1000, IHC 1:150

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.