Iduronate 2 sulfatase (IDS) Mouse Monoclonal Antibody [Clone ID: LBI1D9]
Product Specifications
Background
Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq]
Overview
IDS (Iduronate 2 sulfatase) mouse monoclonal antibody, clone LBI1D9
Synonyms
MPS2; SIDS
Gene Name
Iduronate 2-sulfatase
Gene ID
3423
UniProt
P22304
Conjugation
Unconjugated
Related Pathways
Glycosaminoglycan degradation, Lysosome, Metabolic pathways
Field of Research
Glycosaminoglycan degradation, Lysosome, Metabolic pathways
Concentration
1 mg/ml
Dilution
WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
IDS
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3423
Uniprot URL
https://www.uniprot.org/uniprot/P22304
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