Proteasome subunit beta type 4 (PSMB4) Mouse Monoclonal Antibody [Clone ID: LBI2H2]
Product Specifications
Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. [provided by RefSeq, Jul
Synonyms
HN3; HsN3; PROS-26; PROS26
Gene Name
Proteasome 20S subunit beta 4
Gene ID
5692
UniProt
P28070
Conjugation
Unconjugated
Related Pathways
Proteasome
Field of Research
Proteasome
Concentration
0.95 mg/ml
Dilution
WB 1:500, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Protease
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PSMB4
Overview
PSMB4 (Proteasome subunit beta type 4) mouse monoclonal antibody, clone LBI2H2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5692
Uniprot URL
https://www.uniprot.org/uniprot/P28070
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