SERPINB6 Mouse Monoclonal Antibody [Clone ID: LBI2F8]

Product Specifications

Background

The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin (ov) -serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

Overview

SERPINB6 mouse monoclonal antibody, clone LBI2F8

Synonyms

CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3

Gene Name

Serpin family B member 6

Gene ID

5269

UniProt

P35237

Conjugation

Unconjugated

Concentration

0.99 mg/ml

Dilution

WB 1:500~2000, IHC 1:150

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.