PFKP Mouse Monoclonal Antibody [Clone ID: LBI2E10]
Product Specifications
Background
The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11) . PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2. [supplied by OMIM]
Synonyms
ATP-PFK; PFK-C; PFK-P; PFKF
Gene Name
Phosphofructokinase, platelet
Gene ID
5214
UniProt
Q01813
Conjugation
Unconjugated
Related Pathways
Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway
Field of Research
Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway
Concentration
0.5 mg/ml
Dilution
WB 1:500~2000, IHC 1:150, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PFKP
Overview
PFKP mouse monoclonal antibody, clone LBI2E10
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5214
Uniprot URL
https://www.uniprot.org/uniprot/Q01813
Curated Selection
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