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Kv beta 1 (KCNAB1) Mouse Monoclonal Antibody [Clone ID: LBI4E7]

Product Specifications

Background

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s) . This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes three distinct isoforms which are encoded by three alternatively spliced transcript variants of this gene. These three isoforms are beta subunits, which form heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq]

Synonyms

AKR6A3; hKvb3; hKvBeta3; KCNA1B; KV-BETA-1; Kvb1.3

Gene Name

Potassium voltage-gated channel subfamily A regulatory beta subunit 1

Gene ID

7881

UniProt

Q14722

Conjugation

Unconjugated

Concentration

0.62 mg/ml

Dilution

WB 1:2000, IHC 1:150

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Ion Channels: Other

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

KCNAB1

Overview

KCNAB1 (Kv beta 1) mouse monoclonal antibody, clone LBI4E7

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=7881

Uniprot URL

https://www.uniprot.org/uniprot/Q14722

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