Cytochrome P450 2C9 (CYP2C9) Mouse Monoclonal Antibody [Clone ID: LBI2C8]
Product Specifications
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul
Synonyms
CPC9; CYP2C; CYP2C10; CYPIIC9; P450IIC9
Gene Name
Cytochrome P450 family 2 subfamily C member 9
Gene ID
1559
UniProt
P11712
Conjugation
Unconjugated
Related Pathways
Arachidonic acid metabolism, Drug metabolism - cytochrome P450, Linoleic acid metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism
Field of Research
Arachidonic acid metabolism, Drug metabolism - cytochrome P450, Linoleic acid metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism
Concentration
0.48 mg/ml
Dilution
WB 1:2000, IHC 1:150, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, P450
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CYP2C9
Overview
CYP2C9 (Cytochrome P450 2C9) mouse monoclonal antibody, clone LBI2C8
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1559
Uniprot URL
https://www.uniprot.org/uniprot/P11712
Curated Selection
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