PTPN7 Mouse Monoclonal Antibody [Clone ID: LBI3B10]
Product Specifications
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
Synonyms
BPTP-4; HEPTP; LC-PTP; LPTP; PTPNI
Gene Name
Protein tyrosine phosphatase non-receptor type 7
Gene ID
5778
UniProt
P35236
Conjugation
Unconjugated
Related Pathways
MAPK signaling pathway
Field of Research
MAPK signaling pathway
Concentration
0.72 mg/ml
Dilution
WB 1:500~2000, IF 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Phosphatase
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PTPN7
Overview
PTPN7 (HePTP) mouse monoclonal antibody, clone LBI3B10
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5778
Uniprot URL
https://www.uniprot.org/uniprot/P35236
Curated Selection
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