DAND5 Mouse Monoclonal Antibody [Clone ID: LBI3A3]
Product Specifications
Background
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq]
Synonyms
CER2; CERL2; CKTSF1B3; COCO; CRL2; DANTE; GREM3; SP1
Gene Name
DAN domain BMP antagonist family member 5
Gene ID
199699
UniProt
Q8N907
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
IF 1:100, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
DAND5
Overview
DAND5 mouse monoclonal antibody, clone LBI3A3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=199699
Uniprot URL
https://www.uniprot.org/uniprot/Q8N907
Curated Selection
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