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Calpain 9 (CAPN9) Mouse Monoclonal Antibody [Clone ID: LBI1C2]

Product Specifications

Background

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Overview

CAPN9 (Calpain 9) mouse monoclonal antibody, clone LBI1C2

Synonyms

GC36; nCL-4

Gene Name

Calpain 9

Gene ID

10753

UniProt

O14815

Conjugation

Unconjugated

Concentration

0.9 mg/ml

Dilution

WB 1:2000, IF 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Protease

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

CAPN9

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=10753

Uniprot URL

https://www.uniprot.org/uniprot/O14815

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