PNPO Mouse Monoclonal Antibody [Clone ID: LBI1G9]

Product Specifications

Background

The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.

Overview

PNPO mouse monoclonal antibody, clone LBI1G9

Synonyms

HEL-S-302; PDXPO

Gene Name

Pyridoxamine 5'-phosphate oxidase

Gene ID

55163

UniProt

Q9NVS9

Conjugation

Unconjugated

Related Pathways

Metabolic pathways, Vitamin B6 metabolism

Field of Research

Metabolic pathways, Vitamin B6 metabolism

Concentration

1 mg/ml

Dilution

WB 1:4000, IHC 1:150, FLOW 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.