PMVK Mouse Monoclonal Antibody [Clone ID: LBI2F9]
Product Specifications
Background
This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis. [provided by RefSeq, Sep 2011]
Synonyms
HUMPMKI; PMK; PMKA; PMKASE; POROK1
Gene Name
Phosphomevalonate kinase
Gene ID
10654
UniProt
Q15126
Conjugation
Unconjugated
Related Pathways
Metabolic pathways, Terpenoid backbone biosynthesis
Field of Research
Metabolic pathways, Terpenoid backbone biosynthesis
Concentration
0.32 mg/ml
Dilution
WB 1:2000, IF 1:100, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PMVK
Overview
PMVK mouse monoclonal antibody, clone LBI2F9
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=10654
Uniprot URL
https://www.uniprot.org/uniprot/Q15126
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