PMVK Mouse Monoclonal Antibody [Clone ID: LBI2F9]

Product Specifications

Background

This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis. [provided by RefSeq, Sep 2011]

Overview

PMVK mouse monoclonal antibody, clone LBI2F9

Synonyms

HUMPMKI; PMK; PMKA; PMKASE; POROK1

Gene Name

Phosphomevalonate kinase

Gene ID

10654

UniProt

Q15126

Conjugation

Unconjugated

Related Pathways

Metabolic pathways, Terpenoid backbone biosynthesis

Field of Research

Metabolic pathways, Terpenoid backbone biosynthesis

Concentration

0.32 mg/ml

Dilution

WB 1:2000, IF 1:100, FLOW 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.