PDE4 (PDE4B) Mouse Monoclonal Antibody [Clone ID: LBI2B10]

Product Specifications

Background

This gene is a member of the type IV, cyclic AMP (cAMP) -specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Overview

PDE4B mouse monoclonal antibody, clone LBI2B10

Synonyms

DPDE4; PDE4B5; PDEIVB

Gene Name

Phosphodiesterase 4B

Gene ID

5142

UniProt

Q07343

Conjugation

Unconjugated

Related Pathways

Progesterone-mediated oocyte maturation, Purine metabolism

Field of Research

Progesterone-mediated oocyte maturation, Purine metabolism

Concentration

0.53 mg/ml

Dilution

WB 1:2000, FLOW 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.