Cytochrome P450 17A1 (CYP17A1) Mouse Monoclonal Antibody [Clone ID: LBI3F11]
Product Specifications
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008]
Synonyms
CPT7; CYP17; P450C17; S17AH
Gene Name
Cytochrome P450 family 17 subfamily A member 1
Gene ID
1586
UniProt
P05093
Conjugation
Unconjugated
Related Pathways
C21-Steroid hormone metabolism, Metabolic pathways
Field of Research
C21-Steroid hormone metabolism, Metabolic pathways
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:150, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, P450
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CYP17A1
Overview
CYP17A1 mouse monoclonal antibody, clone LBI3F11
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1586
Uniprot URL
https://www.uniprot.org/uniprot/P05093
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
