Apc2 (ANAPC2) Mouse Monoclonal Antibody [Clone ID: LBI1H8]
Product Specifications
Background
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. [provided by RefSeq]
Synonyms
APC2
Gene Name
Anaphase promoting complex subunit 2
Gene ID
29882
UniProt
Q9UJX6
Conjugation
Unconjugated
Related Pathways
Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, Ubiquitin mediated proteolysis
Field of Research
Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, Ubiquitin mediated proteolysis
Concentration
0.38 mg/ml
Dilution
WB 1:500~2000, IF 1:100, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
ANAPC2
Overview
ANAPC2 (Apc2) mouse monoclonal antibody, clone LBI1H8
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=29882
Uniprot URL
https://www.uniprot.org/uniprot/Q9UJX6
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