XPF (ERCC4) Mouse Monoclonal Antibody [Clone ID: LBI1B2]

Product Specifications

Background

The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6) .

Overview

ERCC4 mouse monoclonal antibody, clone LBI1B2

Synonyms

ERCC11; FANCQ; RAD1; XFEPS; XPF

Gene Name

ERCC excision repair 4, endonuclease catalytic subunit

Gene ID

2072

UniProt

Q92889

Conjugation

Unconjugated

Related Pathways

Nucleotide excision repair

Field of Research

Nucleotide excision repair

Concentration

1 mg/ml

Dilution

WB 1:500, IF 1:100, FLOW 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.