SOCS3 Mouse Monoclonal Antibody [Clone ID: LBI15F9]
Product Specifications
Background
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN) -gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq]
Overview
SOCS3 mouse monoclonal antibody, clone LBI15F9
Synonyms
ATOD4; CIS3; Cish3; SOCS-3; SSI-3; SSI3
Gene Name
Suppressor of cytokine signaling 3
Gene ID
9021
UniProt
O14543
Conjugation
Unconjugated
Related Pathways
Adipocytokine signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, Type II diabetes mellitus, Ubiquitin mediated proteolysis
Field of Research
Adipocytokine signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, Type II diabetes mellitus, Ubiquitin mediated proteolysis
Concentration
0.81 mg/ml
Dilution
WB 1:2000, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
SOCS3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=9021
Uniprot URL
https://www.uniprot.org/uniprot/O14543
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