STAT4 Mouse Monoclonal Antibody [Clone ID: LBI2F3]
Product Specifications
Background
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug
Synonyms
SLEB11
Gene Name
Signal transducer and activator of transcription 4
Gene ID
6775
UniProt
Q14765
Conjugation
Unconjugated
Related Pathways
Jak-STAT signaling pathway
Field of Research
Jak-STAT signaling pathway
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
STAT4
Overview
STAT4 mouse monoclonal antibody, clone LBI2F3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6775
Uniprot URL
https://www.uniprot.org/uniprot/Q14765
Curated Selection
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