AP2M1 Mouse Monoclonal Antibody [Clone ID: LBI1B11]

Product Specifications

Background

This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Overview

AP2M1 mouse monoclonal antibody, clone LBI1B11

Synonyms

AP50; CLAPM1; mu2

Gene Name

Adaptor related protein complex 2 subunit mu 1

Gene ID

1173

UniProt

Q96CW1

Conjugation

Unconjugated

Related Pathways

Endocytosis, Huntington's disease

Field of Research

Endocytosis, Huntington's disease

Concentration

0.75 mg/ml

Dilution

WB 1:500~2000, IF 1:100, FLOW 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.