PBX1 Mouse Monoclonal Antibody [Clone ID: LBI1D9]
Product Specifications
Background
This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t (1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms
DKFZp686B09108; MGC126627
Gene Name
PBX homeobox 1
Gene ID
5087
UniProt
P40424
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:2000, IF 1:100, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Stem cell - Pluripotency, Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PBX1
Overview
PBX1 mouse monoclonal antibody, clone LBI1D9
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5087
Uniprot URL
https://www.uniprot.org/uniprot/P40424
Curated Selection
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