STAT4 Mouse Monoclonal Antibody [Clone ID: LBI 1H3]

Product Specifications

Background

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug

Overview

STAT4 mouse monoclonal antibody, clone LBI 1H3

Synonyms

SLEB11

Gene Name

Signal transducer and activator of transcription 4

Gene ID

6775

UniProt

Q14765

Conjugation

Unconjugated

Related Pathways

Jak-STAT signaling pathway

Field of Research

Jak-STAT signaling pathway

Concentration

0.36 mg/ml

Dilution

WB 1:2000, IHC 1:150, IF 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Transcription Factors

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.