SNAP25 Mouse Monoclonal Antibody [Clone ID: LBI4G5]
Product Specifications
Background
Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs) . The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq]
Synonyms
CMS18; RIC-4; RIC4; SEC9; SNAP; SNAP-25; SUP; bA416N4.2; dJ1068F16.2
Gene Name
Synaptosome associated protein 25
Gene ID
6616
UniProt
P60880
Conjugation
Unconjugated
Related Pathways
SNARE interactions in vesicular transport
Field of Research
SNARE interactions in vesicular transport
Concentration
0.9 mg/ml
Dilution
WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
SNAP25
Overview
SNAP25 mouse monoclonal antibody, clone LBI4G5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6616
Uniprot URL
https://www.uniprot.org/uniprot/P60880
Curated Selection
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