LNK (SH2B3) Mouse Monoclonal Antibody [Clone ID: LBI1E6]

Product Specifications

Background

This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.

Overview

SH2B3 (LNK) mouse monoclonal antibody, clone LBI1E6

Synonyms

IDDM20; LNK

Gene Name

SH2B adaptor protein 3

Gene ID

10019

UniProt

Q9UQQ2

Conjugation

Unconjugated

Related Pathways

Neurotrophin signaling pathway

Field of Research

Neurotrophin signaling pathway

Concentration

0.6 mg/ml

Dilution

WB 1:2000, IF 1:100, FLOW 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.