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VASP Mouse Monoclonal Antibody [Clone ID: LBI1C3]

Product Specifications

Background

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq]

Overview

VASP mouse monoclonal antibody, clone LBI1C3

Synonyms

Vasodilator-stimulated phosphoprotein

Gene Name

Vasodilator stimulated phosphoprotein

Gene ID

7408

UniProt

P50552

Conjugation

Unconjugated

Related Pathways

Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration

Field of Research

Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration

Concentration

0.45 mg/ml

Dilution

WB 1:500~2000, IF 1:100, FLOW 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Stem cell - Pluripotency

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

VASP

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=7408

Uniprot URL

https://www.uniprot.org/uniprot/P50552

Frequently Asked Questions

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