POLR2J2 Mouse Monoclonal Antibody [Clone ID: LBI3G4]
Product Specifications
Background
This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD) . Consequently, it is not known if this locus expresses a protein or proteins in vivo. [provided by RefSeq]
Synonyms
HRPB11B; RPB11b1
Gene Name
RNA polymerase II subunit J2
Gene ID
246721
UniProt
Q9GZM3
Conjugation
Unconjugated
Related Pathways
Huntington's disease, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase
Field of Research
Huntington's disease, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase
Concentration
0.72 mg/ml
Dilution
WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
POLR2J2
Overview
POLR2J2 mouse monoclonal antibody, clone LBI3G4
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=246721
Uniprot URL
https://www.uniprot.org/uniprot/Q9GZM3
Curated Selection
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