ERK5 (MAPK7) Mouse Monoclonal Antibody [Clone ID: LBI1A4]
Product Specifications
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5) . It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq]
Synonyms
BMK1; ERK4; ERK5; PRKM7
Gene Name
Mitogen-activated protein kinase 7
Gene ID
5598
UniProt
Q13164
Conjugation
Unconjugated
Related Pathways
Gap junction, GnRH signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway
Field of Research
Gap junction, GnRH signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway
Concentration
0.84 mg/ml
Dilution
WB 1:500, IF 1:100, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Protein Kinase
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
MAPK7
Overview
MAPK7 (ERK5) mouse monoclonal antibody, clone LBI1A4
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5598
Uniprot URL
https://www.uniprot.org/uniprot/Q13164
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