MYD88 Mouse Monoclonal Antibody [Clone ID: LBI1A10]

Product Specifications

Background

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq]

Overview

MYD88 mouse monoclonal antibody, clone LBI1A10

Synonyms

MYD88D

Gene Name

MYD88 innate immune signal transduction adaptor

Gene ID

4615

UniProt

Q99836

Conjugation

Unconjugated

Related Pathways

Apoptosis, Toll-like receptor signaling pathway

Field of Research

Apoptosis, Toll-like receptor signaling pathway

Concentration

0.72 mg/ml

Dilution

WB 1:2000, IHC 1:150, FLOW 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.