MYD88 Mouse Monoclonal Antibody [Clone ID: LBI1A10]
Product Specifications
Background
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq]
Synonyms
MYD88D
Gene Name
MYD88 innate immune signal transduction adaptor
Gene ID
4615
UniProt
Q99836
Conjugation
Unconjugated
Related Pathways
Apoptosis, Toll-like receptor signaling pathway
Field of Research
Apoptosis, Toll-like receptor signaling pathway
Concentration
0.72 mg/ml
Dilution
WB 1:2000, IHC 1:150, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
MYD88
Overview
MYD88 mouse monoclonal antibody, clone LBI1A10
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4615
Uniprot URL
https://www.uniprot.org/uniprot/Q99836
Curated Selection
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