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LMAN1 Mouse Monoclonal Antibody [Clone ID: LBI2B10]

Product Specifications

Background

The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq]

Synonyms

ERGIC-53; ERGIC53; F5F8D; FMFD1; gp58; MCFD1; MR60

Gene Name

Lectin, mannose binding 1

Gene ID

3998

UniProt

P49257

Conjugation

Unconjugated

Concentration

0.59 mg/ml

Dilution

WB 1:200~500, IF 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

LMAN1

Overview

LMAN1 mouse monoclonal antibody, clone LBI2B10

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=3998

Uniprot URL

https://www.uniprot.org/uniprot/P49257

Curated Selection

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