KEAP1 Mouse Monoclonal Antibody [Clone ID: LBI1B4]
Product Specifications
Background
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq]
Synonyms
INrf2; KIAA0132; KLHL19; MGC1114; MGC4407; MGC9454; MGC10630; MGC20887
Gene Name
Kelch like ECH associated protein 1
Gene ID
9817
UniProt
Q14145
Conjugation
Unconjugated
Related Pathways
Ubiquitin mediated proteolysis
Field of Research
Ubiquitin mediated proteolysis
Concentration
1 mg/ml
Dilution
WB 1:500~2000, IHC 1:150, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
KEAP1
Overview
KEAP1 mouse monoclonal antibody, clone LBI1B4
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=9817
Uniprot URL
https://www.uniprot.org/uniprot/Q14145
Curated Selection
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