Bestrophin 3 (BEST3) Mouse Monoclonal Antibody [Clone ID: LBI3B11]
Product Specifications
Background
BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336) . Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]) . [supplied by OMIM]
Synonyms
VMD2L3
Gene Name
Bestrophin 3
Gene ID
144453
UniProt
Q8N1M1
Conjugation
Unconjugated
Concentration
0.47 mg/ml
Dilution
WB 1:2000, IF 1:100, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Ion Channels: Other, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
BEST3
Overview
BEST3 (Bestrophin 3) mouse monoclonal antibody, clone LBI3B11
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=144453
Uniprot URL
https://www.uniprot.org/uniprot/Q8N1M1
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