PIK3AP1 Mouse Monoclonal Antibody [Clone ID: LBI7B12]
Product Specifications
Background
Involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. Seems to have a complementary role with CD19 in PI3K activation (By similarity) . May be involved in the survival of mature B cells via activation of REL (By similarity) .
Overview
Anti-PIK3AP1 mouse monoclonal antibody, clone LBI7B12
Synonyms
BCAP
Gene Name
Phosphoinositide-3-kinase adaptor protein 1
Gene ID
118788
UniProt
Q6ZUJ8
Conjugation
Unconjugated
Related Pathways
B cell receptor signaling pathway
Field of Research
B cell receptor signaling pathway
Concentration
0.4 mg/ml
Dilution
WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PIK3AP1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=118788
Uniprot URL
https://www.uniprot.org/uniprot/Q6ZUJ8
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