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B7-1 (CD80) Mouse Monoclonal Antibody [Clone ID: LBI2B11]

Product Specifications

Background

The B-lymphocyte activation antigen B7-1 (formerly referred to as B7) provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 (MIM 186760) and CTLA4 (MIM 123890) ligands of T cells. [supplied by OMIM]

Synonyms

B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7

Gene Name

CD80 molecule

Gene ID

941

UniProt

P33681

Conjugation

Unconjugated

Related Pathways

Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis

Field of Research

Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis

Concentration

1 mg/ml

Dilution

WB 1:2000, IHC 1:150, IF 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Transcription Factors, Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

CD80

Overview

CD80 mouse monoclonal antibody, clone LBI2B11

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=941

Uniprot URL

https://www.uniprot.org/uniprot/P33681

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