QPRT Mouse Monoclonal Antibody [Clone ID: LBI4B3]
Product Specifications
Background
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Synonyms
HEL-S-90n; QPRTase
Gene Name
Quinolinate phosphoribosyltransferase
Gene ID
23475
UniProt
Q15274
Conjugation
Unconjugated
Related Pathways
Metabolic pathways, Nicotinate and nicotinamide metabolism
Field of Research
Metabolic pathways, Nicotinate and nicotinamide metabolism
Concentration
0.39 mg/ml
Dilution
WB 1:500~2000, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
QPRT
Overview
Anti-QPRT mouse monoclonal antibody, clone LBI4B3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=23475
Uniprot URL
https://www.uniprot.org/uniprot/Q15274
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