PAICS Mouse Monoclonal Antibody [Clone ID: LBI1B4]

Product Specifications

Background

This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Overview

PAICS mouse monoclonal antibody, clone LBI1B4

Synonyms

ADE2; ADE2H1; AIRC; PAIS

Gene Name

Phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase

Gene ID

10606

UniProt

P22234

Conjugation

Unconjugated

Related Pathways

Metabolic pathways, Purine metabolism

Field of Research

Metabolic pathways, Purine metabolism

Concentration

1 mg/ml

Dilution

WB 1:2000, IF 1:100, FLOW 1:100

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.