TBXAS1 Mouse Monoclonal Antibody [Clone ID: LBI1A12]
Product Specifications
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms
BDPLT14; CYP5; CYP5A1; GHOSAL; THAS; TS; TXAS; TXS
Gene Name
Thromboxane A synthase 1
Gene ID
6916
UniProt
P24557
Conjugation
Unconjugated
Related Pathways
Arachidonic acid metabolism, Metabolic pathways
Field of Research
Arachidonic acid metabolism, Metabolic pathways
Concentration
0.8 mg/ml
Dilution
WB 1:2000, IF 1:100, FLOW 1:100
Form
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, P450
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
TBXAS1
Overview
Anti-TBXAS1 (Thromboxane synthase) mouse monoclonal antibody, clone LBI1A12
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6916
Uniprot URL
https://www.uniprot.org/uniprot/P24557
Curated Selection
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