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TBXAS1 Mouse Monoclonal Antibody [Clone ID: LBI2C1]

Product Specifications

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Overview

Anti-TBXAS1 (Thromboxane synthase) mouse monoclonal antibody, clone LBI2C1

Synonyms

BDPLT14; CYP5; CYP5A1; GHOSAL; THAS; TS; TXAS; TXS

Gene Name

Thromboxane A synthase 1

Gene ID

6916

UniProt

P24557

Conjugation

Unconjugated

Related Pathways

Arachidonic acid metabolism, Metabolic pathways

Field of Research

Arachidonic acid metabolism, Metabolic pathways

Concentration

0.86 mg/ml

Dilution

WB 1:1000~2000, IHC 1:50, IF 1:100, FLOW 1:100

Form

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, P450

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

TBXAS1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=6916

Uniprot URL

https://www.uniprot.org/uniprot/P24557

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